Wednesday, March 11, 2015

Human Adaptation to Arsenic-Rich Environments



Photo credit: Gerth Michael via wikimedia commons. The mountains around San Antonia de los Cobres .

What is more cool than read about environmental adaptation in humans?
An isolated group of people living in the Andes have developed a tolerance to arsenic in their water supply. The discovery is not only the first time humans have been found to have adapted to arsenic, but it is also “the first known case of humans selection for tolerance to a toxic chemical”, according to the paper.
Investigators conducted a study of residents in the northern Argentinean town of San Antonio de los Cobres. The area is dry and volcanic eruptions have left an arsenic residue that has entered the local water supply. The residents have inadvertently responded by evolving the capacity to methylate arsenic, reducing its toxicity and making it easier to excrete. They found that there was a strong association between the capacity of people in the area to process arsenic in this way and the expression of the AS3MT gene (i.e. it producing an enzyme that enables arsenic metabolism). However, this is the first time a population has been found with such high rates of AS3MT expression. Those studied were also particularly likely to have unusual variations in genes located near the AS3MT gene.
When: 10:30 March 17, 2015



Where: Argumentet, Ekologihuset 2nd floor

And Of course, Fika will be provided!

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