Posted by Anna Nordén
This coming lab meeting (Tuesday April 29th), we
will discuss sexual selection and sexual conflict on the chromosome level. I
have chosen a paper that deals with mito-sex chromosome interactions,
inter-genomic coadaptation and conflict. Looking forward to some interesting
discussions.
Authors: Rebecca Dean, Fabian Zimmer and Judith E. Mank
Abstract: Mitochondrial interactions with the nuclear genome
represent one of life’s most important coevolved mutualisms. In many organisms,
mitochondria are maternally inherited, and in these cases, co-transmission
between the mitochondrial and nuclear genes differs across different parts of
the nuclear genome, with genes on the X chromosome having 2/3 probability of
co-transmission, compared to 1/2 for genes on autosomes. These asymmetrical
inheritance patterns of mitochondria and different parts of the nuclear genome
have the potential to put certain gene combinations in inter-genomic
coadaptation or conflict. Previous work in mammals found strong evidence that
the X chromosome has a dearth of genes that interact with the mitochondria
(mito-nuclear genes), suggesting that inter-genomic conflict might drive genes
off the X onto the autosomes for their male-beneficial effects. Here, we
developed this idea to test co-adaptation and conflict between mito-nuclear
gene combinations across phylogenetically independent sex chromosomes on a far
broader scale. We found that, in addition to therian mammals, only C. elegans
showed an under-representation of mito-nuclear genes on the sex chromosomes.
The remaining species studied showed no overall bias in their distribution of
mito-nuclear genes. We discuss possible factors other than inter-genomic
conflict that might drive the genomic distribution of mito- nuclear genes.
In Argumentet (Ecology Building 2nd floor) at
11:30 – 12 as usual. I will bring fika!
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